- 产品信息
商品描述
靶点-Target
KCNK4
反应性
Human,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
45kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human KCNK4. AA range:332-381
特异性
TRAAK Polyclonal Antibody detects endogenous levels of TRAAK protein.
基因名称
KCNK4
蛋白名称
Potassium channel subfamily K member 4
别名
KCNK4;TRAAK;Potassium channel subfamily K member 4;TWIK-related arachidonic acid-stimulated potassium channel protein;TRAAK;Two pore potassium channel KT4.1;Two pore K;+;channel KT4.1
Organism-1
Human
基因ID-1
50801
SwissProt-1
Q9NYG8
Organism-2
Mouse
基因ID-2
16528
SwissProt-2
O88454
背景
This gene encodes a member of the TWIK-related arachidonic acid-stimulated two pore potassium channel subfamily. The encoded protein homodimerizes and functions as an outwardly rectifying channel. This channel is regulated by polyunsaturated fatty acids, temperature and mechanical deformation of the lipid membrane. This protein is expressed primarily in neural tissues and may be involved in regulating the noxious input threshold in dorsal root ganglia neurons. Alternate splicing results in multiple transcript variants. Naturally occurring read-through transcripts also exist between this gene and the downstream testis expressed 40 (TEX40) gene, as represented in GeneID: 106780802. [provided by RefSeq, Nov 2015],
细胞定位
Cell membrane ; Multi-pass membrane protein .





