FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
TP53INP1
反应性
Human
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
27kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human TP53INP1. AA range:171-220
特异性
TP53INP1 Polyclonal Antibody detects endogenous levels of TP53INP1 protein.
基因名称
TP53INP1
蛋白名称
Tumor protein p53-inducible nuclear protein 1
别名
TP53INP1;P53DINP1;SIP;Tumor protein p53-inducible nuclear protein 1;Stress-induced protein;p53-dependent damage-inducible nuclear protein 1;p53DINP1
Organism-1
Human
基因ID-1
94241
SwissProt-1
Q96A56
Organism-2
Mouse
SwissProt-2
Q9QXE4
背景
function:In response to double-strand DNA breaks, promotes p53/TP53 phosphorylation on 'Ser-46' and subsequent apoptosis.,induction:By adriamycin, gamma irradiation and H(2)O(2), in a p53-dependent way. At lower levels by ultraviolet irradiation.,subcellular location:Concentrated in PML/POD/ND10 nuclear bodies.,subunit:Interacts with TP53 and HIPK2.,tissue specificity:Ubiquitously expressed.,
细胞定位
Cytoplasm, cytosol. Nucleus. Nucleus, PML body. Cytoplasmic vesicle, autophagosome. Shuttles between the nucleus and the cytoplasm, depending on cellular stress conditions, and re-localizes to autophagosomes on autophagy activation.
