FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Topo I
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
90kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from the Internal region of human Topo I.
特异性
Topo I Polyclonal Antibody detects endogenous levels of Topo I protein.
基因名称
TOP1
蛋白名称
DNA topoisomerase 1
别名
TOP1;DNA topoisomerase 1;DNA topoisomerase I
Organism-1
Human
基因ID-1
7150
SwissProt-1
P11387
Organism-2
Mouse
基因ID-2
21969
SwissProt-2
Q04750
Organism-3
Rat
基因ID-3
64550
SwissProt-3
Q9WUL0
背景
This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus, nucleolus . Nucleus, nucleoplasm . Diffuse nuclear localization with some enrichment in nucleoli. On CPT treatment, cleared from nucleoli into nucleoplasm. Sumoylated forms found in both nucleoplasm and nucleoli.
