TNF-β Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2616569

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商品描述
  • 靶点-Target

    TNFB

  • 反应性

    Human,Mouse,Rat,Monkey

  • 应用

    WB,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    22kD

  • 推荐稀释比

    WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human TNF-beta. AA range:17-66

  • 特异性

    TNF-β Polyclonal Antibody detects endogenous levels of TNF-β protein.

  • 基因名称

    LTA

  • 蛋白名称

    Lymphotoxin-alpha

  • 别名

    LTA;TNFB;TNFSF1;Lymphotoxin-alpha;LT-alpha;TNF-beta;Tumor necrosis factor ligand superfamily member 1

  • Organism-1

    Human

  • 基因ID-1

    4049

  • SwissProt-1

    P01374

  • Organism-2

    Mouse

  • 基因ID-2

    16992

  • SwissProt-2

    P09225

  • Organism-3

    Rat

  • 基因ID-3

    25008

  • SwissProt-3

    Q06332

  • 背景

    The encoded protein, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. The protein is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. This protein also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Genetic variations in this gene are associated with susceptibility to leprosy type 4, myocardial infarction, non-Hodgkin's lymphoma, and psoriatic arthritis. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jul 2012],

  • 细胞定位

    Secreted. Membrane. The homotrimer is secreted. The heterotrimer is membrane-associated.