- 产品信息
商品描述
靶点-Target
TNFB
反应性
Human,Mouse,Rat,Monkey
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
22kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human TNF-beta. AA range:17-66
特异性
TNF-β Polyclonal Antibody detects endogenous levels of TNF-β protein.
基因名称
LTA
蛋白名称
Lymphotoxin-alpha
别名
LTA;TNFB;TNFSF1;Lymphotoxin-alpha;LT-alpha;TNF-beta;Tumor necrosis factor ligand superfamily member 1
Organism-1
Human
基因ID-1
4049
SwissProt-1
P01374
Organism-2
Mouse
基因ID-2
16992
SwissProt-2
P09225
Organism-3
Rat
基因ID-3
25008
SwissProt-3
Q06332
背景
The encoded protein, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. The protein is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. This protein also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Genetic variations in this gene are associated with susceptibility to leprosy type 4, myocardial infarction, non-Hodgkin's lymphoma, and psoriatic arthritis. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jul 2012],
细胞定位
Secreted. Membrane. The homotrimer is secreted. The heterotrimer is membrane-associated.





