FGF-2 Polyclonal Antibody
¥680.00
TNF-IP 8L2 Polyclonal Antibody
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2616564
- 产品信息
商品描述
靶点-Target
TNF-IP 8L2
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
20kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human TNFAIP8L2. AA range:11-60
特异性
TNF-IP 8L2 Polyclonal Antibody detects endogenous levels of TNF-IP 8L2 protein.
基因名称
TNFAIP8L2
蛋白名称
Tumor necrosis factor alpha-induced protein 8-like protein 2
别名
TNFAIP8L2;Tumor necrosis factor alpha-induced protein 8-like protein 2;TIPE2;TNF alpha-induced protein 8-like protein 2;TNFAIP8-like protein 2;Inflammation factor protein 20
Organism-1
Human
基因ID-1
79626
SwissProt-1
Q6P589
Organism-2
Mouse
基因ID-2
69769
SwissProt-2
Q9D8Y7
Organism-3
Rat
基因ID-3
310663
SwissProt-3
Q6AYJ8
背景
domain:The central region was initially thought to constitute a DED (death effector) domain. However, 3D-structure data reveal a previously uncharacterized fold that is different from the predicted fold of a DED (death effector) domain. It consists of a large, hydrophobic central cavity that is poised for cofactor binding.,function:Acts as a negative regulator of innate and adaptive immunity by maintaining immune homeostasis. Negative regulator of Toll-like receptor and T-cell receptor function. Prevents hyperresponsiveness of the immune system and maintains immune homeostasis. Inhibits jun/ap1 and NF-kappa-B activation. Promotes Fas-induced apoptosis.,similarity:Belongs to the TNFAIP8 family. TNFAIP8L2 subfamily.,subunit:May interact with CASP8; however, such result is unclear since PubMed:19079267 could not reproduce the interaction with CASP8.,
细胞定位
cytoplasm,
