FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
TMPRSS3
反应性
Human,Mouse
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
49kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human TMPRSS3. AA range:405-454
特异性
TMPRSS3 Polyclonal Antibody detects endogenous levels of TMPRSS3 protein.
基因名称
TMPRSS3
蛋白名称
Transmembrane protease serine 3
别名
TMPRSS3;ECHOS1;TADG12;Transmembrane protease serine 3;Serine protease TADG-12;Tumor-associated differentially-expressed gene 12 protein
Organism-1
Human
基因ID-1
64699
SwissProt-1
P57727
Organism-2
Mouse
基因ID-2
140765
SwissProt-2
Q8K1T0
背景
This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a serine protease domain, a transmembrane domain, an LDL receptor-like domain, and a scavenger receptor cysteine-rich domain. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. This gene was identified by its association with both congenital and childhood onset autosomal recessive deafness. This gene is expressed in fetal cochlea and many other tissues, and is thought to be involved in the development and maintenance of the inner ear or the contents of the perilymph and endolymph. This gene was also identified as a tumor-associated gene that is overexpressed in ovarian tumors. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2012],
细胞定位
Endoplasmic reticulum membrane ; Single-pass type II membrane protein .
