FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
TMC8
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
81kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human TMC8. AA range:601-650
特异性
TMC8 Polyclonal Antibody detects endogenous levels of TMC8 protein.
基因名称
TMC8
蛋白名称
Transmembrane channel-like protein 8
别名
TMC8;EVER2;EVIN2;Transmembrane channel-like protein 8;Epidermodysplasia verruciformis protein 2
Organism-1
Human
基因ID-1
147138
SwissProt-1
Q8IU68
Organism-2
Mouse
基因ID-2
217356
SwissProt-2
Q7TN58
背景
Epidermodysplasia verruciformis (EV) is an autosomal recessive dermatosis characterized by abnormal susceptibility to human papillomaviruses (HPVs) and a high rate of progression to squamous cell carcinoma on sun-exposed skin. EV is caused by mutations in either of two adjacent genes located on chromosome 17q25.3. Both of these genes encode integral membrane proteins that localize to the endoplasmic reticulum and are predicted to form transmembrane channels. This gene encodes a transmembrane channel-like protein with 8 predicted transmembrane domains and 3 leucine zipper motifs. [provided by RefSeq, Jul 2008],
细胞定位
Endoplasmic reticulum membrane ; Multi-pass membrane protein .
