FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
TIS11B
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
36kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human TISB. AA range:58-107
特异性
TIS11B Polyclonal Antibody detects endogenous levels of TIS11B protein.
基因名称
ZFP36L1
蛋白名称
Zinc finger protein 36 C3H1 type-like 1
别名
ZFP36L1;BERG36;BRF1;ERF1;RNF162B;TIS11B;Zinc finger protein 36;C3H1 type-like 1;Butyrate response factor 1;EGF-response factor 1;ERF-1;Protein TIS11B
Organism-1
Human
基因ID-1
677
SwissProt-1
Q07352
Organism-2
Mouse
基因ID-2
12192
SwissProt-2
P23950
Organism-3
Rat
基因ID-3
29344
SwissProt-3
P17431
背景
This gene is a member of the TIS11 family of early response genes, which are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. This gene is well conserved across species and has a promoter that contains motifs seen in other early-response genes. The encoded protein contains a distinguishing putative zinc finger domain with a repeating cys-his motif. This putative nuclear transcription factor most likely functions in regulating the response to growth factors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011],
细胞定位
Nucleus . Cytoplasm . Cytoplasmic granule . Cytoplasm, P-body . Shuttles between the nucleus and the cytoplasm in a XPO1/CRM1-dependent manner (By similarity). Component of cytoplasmic stress granules (PubMed:15967811). Localizes in processing bodies (PBs) (PubMed:17369404). .
