- 产品信息
商品描述
靶点-Target
TIN2
反应性
Human,Mouse
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
53kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human TINF2. AA range:71-120
特异性
TIN2 Polyclonal Antibody detects endogenous levels of TIN2 protein.
基因名称
TINF2
蛋白名称
TERF1-interacting nuclear factor 2
别名
TINF2;TIN2;TERF1-interacting nuclear factor 2;TRF1-interacting nuclear protein 2
Organism-1
Human
基因ID-1
26277
SwissProt-1
Q9BSI4
Organism-2
Mouse
SwissProt-2
Q9QXG9
背景
This gene encodes one of the proteins of the shelterin, or telosome, complex which protects telomeres by allowing the cell to distinguish between telomeres and regions of DNA damage. The protein encoded by this gene is a critical part of shelterin; it interacts with the three DNA-binding proteins of the shelterin complex, and it is important for assembly of the complex. Mutations in this gene cause dyskeratosis congenita (DKC), an inherited bone marrow failure syndrome. [provided by RefSeq, Mar 2010],
细胞定位
Nucleus . Chromosome, telomere . Associated with telomeres.; [Isoform 1]: Nucleus matrix .





