- 产品信息
商品描述
靶点-Target
TIMP-3
反应性
Human,Mouse,Rat
应用
WB,ELISA,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
25kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human TIMP3. AA range:91-140
特异性
TIMP-3 Polyclonal Antibody detects endogenous levels of TIMP-3 protein.
基因名称
TIMP3
蛋白名称
Metalloproteinase inhibitor 3
别名
TIMP3;Metalloproteinase inhibitor 3;Protein MIG-5;Tissue inhibitor of metalloproteinases 3;TIMP-3
Organism-1
Human
基因ID-1
7078
SwissProt-1
P35625
Organism-2
Mouse
基因ID-2
21859
SwissProt-2
P39876
Organism-3
Rat
SwissProt-3
P48032
背景
This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix (ECM). Expression of this gene is induced in response to mitogenic stimulation and this netrin domain-containing protein is localized to the ECM. Mutations in this gene have been associated with the autosomal dominant disorder Sorsby's fundus dystrophy. [provided by RefSeq, Jul 2008],
细胞定位
Secreted, extracellular space, extracellular matrix.





