FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
TIMP1
反应性
Human,Mouse,Rat,Rabbit
应用
IF,WB,IHC,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
24kD
推荐稀释比
IF 1:50-200;WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications;
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human TIMP1. AA range:61-110
特异性
TIMP-1 Polyclonal Antibody detects endogenous levels of TIMP-1 protein.
基因名称
TIMP1
蛋白名称
Metalloproteinase inhibitor 1
别名
TIMP1;CLGI;TIMP;Metalloproteinase inhibitor 1;Erythroid-potentiating activity;EPA;Fibroblast collagenase inhibitor;Collagenase inhibitor;Tissue inhibitor of metalloproteinases 1;TIMP-1
Organism-1
Human
基因ID-1
7076
SwissProt-1
P01033
Organism-2
Mouse
基因ID-2
21857
SwissProt-2
P12032
Organism-3
Rat
基因ID-3
116510
SwissProt-3
P30120
背景
This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. [provided by RefSeq, Jul 2008],
细胞定位
Secreted .
