FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
TIMAP
反应性
Human,Mouse
应用
WB,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
64kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human PPP1R16B. AA range:364-413
特异性
TIMAP Polyclonal Antibody detects endogenous levels of TIMAP protein.
基因名称
PPP1R16B
蛋白名称
Protein phosphatase 1 regulatory inhibitor subunit 16B
别名
PPP1R16B;ANKRD4;KIAA0823;Protein phosphatase 1 regulatory inhibitor subunit 16B;Ankyrin repeat domain-containing protein 4;CAAX box protein TIMAP;TGF-beta-inhibited membrane-associated protein;hTIMAP
Organism-1
Human
基因ID-1
26051
SwissProt-1
Q96T49
Organism-2
Mouse
基因ID-2
228852
SwissProt-2
Q8VHQ3
背景
The protein encoded by this gene is membrane-associated and contains five ankyrin repeats, a protein phosphatase-1-interacting domain, and a carboxy-terminal CAAX box domain. Synthesis of the encoded protein is inhibited by transforming growth factor beta-1. The protein may bind to the membrane through its CAAX box domain and may act as a signaling molecule through interaction with protein phosphatase-1. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein. [provided by RefSeq, Sep 2015],
细胞定位
Cell membrane . Cell membrane ; Lipid-anchor . Nucleus . Cell projection . Colocalizes with RPSA/LAMR1 in the cell membrane (PubMed:16263087). Localizes to the perinuclear region (By similarity). Colocalizes with PTEN at the tip of EC projections (PubMed:25007873). .
