FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Tie-1
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
130kD
推荐稀释比
IHC: 100-300;WB 1:500-1:2000;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human TIE1. AA range:851-900
特异性
Tie-1 Polyclonal Antibody detects endogenous levels of Tie-1 protein.
基因名称
TIE1
蛋白名称
Tyrosine-protein kinase receptor Tie-1
别名
TIE1;TIE;Tyrosine-protein kinase receptor Tie-1
Organism-1
Human
基因ID-1
7075
SwissProt-1
P35590
Organism-2
Mouse
基因ID-2
21846
SwissProt-2
Q06806
背景
This gene encodes a member of the tyrosine protein kinase family. The encoded protein plays a critical role in angiogenesis and blood vessel stability by inhibiting angiopoietin 1 signaling through the endothelial receptor tyrosine kinase Tie2. Ectodomain cleavage of the encoded protein relieves inhibition of Tie2 and is mediated by multiple factors including vascular endothelial growth factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011],
细胞定位
Cell membrane ; Single-pass type I membrane protein .
