FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
TGR5
反应性
Human,Rat,Mouse,
应用
WB,ELISA,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
35kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human GPBAR. AA range:11-60
特异性
TGR5 Polyclonal Antibody detects endogenous levels of TGR5 protein.
基因名称
GPBAR1
蛋白名称
G-protein coupled bile acid receptor 1
别名
GPBAR1;TGR5;G-protein coupled bile acid receptor 1;G-protein coupled receptor GPCR19;hGPCR19;Membrane-type receptor for bile acids;M-BAR;hBG37;BG37
Organism-1
Human
基因ID-1
151306
SwissProt-1
Q8TDU6
Organism-2
Mouse
SwissProt-2
Q80SS6
背景
This gene encodes a member of the G protein-coupled receptor (GPCR) superfamily. This enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP, activation of a MAP kinase signaling pathway, and internalization of the receptor. The receptor is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008],
细胞定位
Cell membrane ; Multi-pass membrane protein .
