FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
TGFB1
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
44-55kD
推荐稀释比
WB 1:500-1:2000;IHC: 1:100-300;ELISA 1:20000;IF 1:100-300;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human TGF beta1. AA range:336-385
特异性
TGFβ1 Polyclonal Antibody detects endogenous levels of TGFβ1 protein.
基因名称
TGFB1 TGFB
蛋白名称
Transforming growth factor beta-1, TGF-β1, TGF b
别名
TGFB1;TGFB;Transforming growth factor beta-1;TGF-beta-1
Organism-1
Human
基因ID-1
7040
SwissProt-1
P01137
Organism-2
Mouse
基因ID-2
21803
SwissProt-2
P04202
Organism-3
Rat
基因ID-3
59086
SwissProt-3
P17246
背景
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGFB family members. This encoded protein regulates cell proliferation, differentiation and growth, and can modulate expression and activation of other growth factors including interferon gamma and tumor necrosis factor alpha. This gene i
细胞定位
[Latency-associated peptide]: Secreted, extracellular space, extracellular matrix .; [Transforming growth factor beta-1]: Secreted .
