TGFβ RIII Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2616511

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商品描述
  • 靶点-Target

    TGFβ RIII

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Calculated)

    93kD

  • 推荐稀释比

    WB 1:500-2000;ELISA 1:5000;IF 1:50-200

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human TGF beta Receptor III. AA range:801-850

  • 特异性

    TGFβ RIII Polyclonal Antibody detects endogenous levels of TGFβ RIII protein.

  • 基因名称

    TGFBR3

  • 蛋白名称

    Transforming growth factor beta receptor type 3

  • 别名

    TGFBR3;Transforming growth factor beta receptor type 3;TGF-beta receptor type 3;TGFR-3;Betaglycan;Transforming growth factor beta receptor III;TGF-beta receptor type III

  • Organism-1

    Human

  • 基因ID-1

    7049

  • SwissProt-1

    Q03167

  • Organism-2

    Mouse

  • 基因ID-2

    21814

  • SwissProt-2

    O88393

  • Organism-3

    Rat

  • 基因ID-3

    29610

  • SwissProt-3

    P26342

  • 背景

    This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.[provided by RefSeq, Sep 2010],

  • 细胞定位

    Secreted. Secreted, extracellular space. Cell membrane ; Single-pass type I membrane protein . Exists both as a membrane-bound form and as soluble form in serum and in the extracellular matrix.