FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
TGF β Receptor I
反应性
Human,Mouse,Rat
应用
WB,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
56kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:20000;IF 1:100-300;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human TGF beta Receptor I. AA range:131-180
特异性
TGFβ RI Polyclonal Antibody detects endogenous levels of TGFβ RI protein.
基因名称
TGFBR1
蛋白名称
TGF-beta receptor type-1
别名
TGFBR1;ALK5;SKR4;TGF-beta receptor type-1;TGFR-1;Activin A receptor type II-like protein kinase of 53kD;Activin receptor-like kinase 5;ALK-5;ALK5;Serine/threonine-protein kinase receptor R4;SKR4;TGF-beta type I receptor;Transfor
Organism-1
Human
基因ID-1
7046
SwissProt-1
P36897
Organism-2
Mouse
基因ID-2
21812
SwissProt-2
Q64729
Organism-3
Rat
SwissProt-3
P80204
背景
The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008],
细胞定位
Cell membrane ; Single-pass type I membrane protein . Cell junction, tight junction . Cell surface . Membrane raft .
