TFIIH p44 Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2616499

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商品描述
  • 靶点-Target

    TFIIH p44

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,IHC,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    62kD

  • 推荐稀释比

    WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:40000;Not yet tested in other applications.

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human TF2H2. AA range:1-50

  • 特异性

    TFIIH p44 Polyclonal Antibody detects endogenous levels of TFIIH p44 protein.

  • 基因名称

    GTF2H2

  • 蛋白名称

    General transcription factor IIH subunit 2

  • 别名

    GTF2H2;BTF2P44;General transcription factor IIH subunit 2;Basic transcription factor 2 44 kDa subunit;BTF2 p44;General transcription factor IIH polypeptide 2;TFIIH basal transcription factor complex p44 subunit

  • Organism-1

    Human

  • 基因ID-1

    2966

  • SwissProt-1

    Q13888

  • Organism-2

    Mouse

  • 基因ID-2

    23894

  • SwissProt-2

    Q9JIB4

  • Organism-3

    Rat

  • 基因ID-3

    294693

  • SwissProt-3

    A0JN27

  • 背景

    This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. This gene is within the telomeric copy of the duplication. Deletion of this gene sometimes accompanies deletion of the neighboring SMN1 gene in spinal muscular atrophy (SMA) patients but it is unclear if deletion of this gene contributes to the SMA phenotype. This gene encodes the 44 kDa subunit of RNA polymerase II transcription initiation factor IIH which is involved in basal transcription and nucleotide excision repair. Transcript variants for this gene have been described, but their full length nature has not been determined. A second copy of t

  • 细胞定位

    Nucleus .