TFIIH p44 Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2616499
- 产品信息
商品描述
靶点-Target
TFIIH p44
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
62kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:40000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human TF2H2. AA range:1-50
特异性
TFIIH p44 Polyclonal Antibody detects endogenous levels of TFIIH p44 protein.
基因名称
GTF2H2
蛋白名称
General transcription factor IIH subunit 2
别名
GTF2H2;BTF2P44;General transcription factor IIH subunit 2;Basic transcription factor 2 44 kDa subunit;BTF2 p44;General transcription factor IIH polypeptide 2;TFIIH basal transcription factor complex p44 subunit
Organism-1
Human
基因ID-1
2966
SwissProt-1
Q13888
Organism-2
Mouse
基因ID-2
23894
SwissProt-2
Q9JIB4
Organism-3
Rat
基因ID-3
294693
SwissProt-3
A0JN27
背景
This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. This gene is within the telomeric copy of the duplication. Deletion of this gene sometimes accompanies deletion of the neighboring SMN1 gene in spinal muscular atrophy (SMA) patients but it is unclear if deletion of this gene contributes to the SMA phenotype. This gene encodes the 44 kDa subunit of RNA polymerase II transcription initiation factor IIH which is involved in basal transcription and nucleotide excision repair. Transcript variants for this gene have been described, but their full length nature has not been determined. A second copy of t
细胞定位
Nucleus .





