TESK1 Polyclonal Antibody

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¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2616490

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商品描述
  • 靶点-Target

    TESK1

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    68kD

  • 推荐稀释比

    WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human TESK1. AA range:181-230

  • 特异性

    TESK1 Polyclonal Antibody detects endogenous levels of TESK1 protein.

  • 基因名称

    TESK1

  • 蛋白名称

    Dual specificity testis-specific protein kinase 1

  • 别名

    TESK1;Dual specificity testis-specific protein kinase 1;Testicular protein kinase 1

  • Organism-1

    Human

  • 基因ID-1

    7016

  • SwissProt-1

    Q15569

  • Organism-2

    Mouse

  • 基因ID-2

    21754

  • SwissProt-2

    O70146

  • Organism-3

    Rat

  • 基因ID-3

    29460

  • SwissProt-3

    Q63572

  • 背景

    testis-specific kinase 1(TESK1) Homo sapiens This gene product is a serine/threonine protein kinase that contains an N-terminal protein kinase domain and a C-terminal proline-rich domain. Its protein kinase domain is most closely related to those of the LIM motif-containing protein kinases (LIMKs). The encoded protein can phosphorylate myelin basic protein and histone in vitro. The testicular germ cell-specific expression and developmental pattern of expression of the mouse gene suggests that this gene plays an important role at and after the meiotic phase of spermatogenesis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015],

  • 细胞定位

    Cytoplasm . Cytoplasm, perinuclear region . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cell projection, lamellipodium . Colocalizes with SPRY4 in vesicular spots in the cytoplasm (PubMed:15584898). Localized to F-actin-rich lamellipodia at the cell periphery following fibronectin-mediated cell adhesion of Schwann cells (By similarity). .