- 产品信息
商品描述
靶点-Target
TdT
反应性
Human,Mouse
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
60kD
推荐稀释比
IHC: 100-300;WB 1:500-1:2000;ELISA 1:40000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human DNTT. AA range:381-430
特异性
TdT Polyclonal Antibody detects endogenous levels of TdT protein.
基因名称
DNTT
蛋白名称
DNA nucleotidylexotransferase
别名
DNTT;TDT;DNA nucleotidylexotransferase;Terminal addition enzyme;Terminal deoxynucleotidyltransferase;Terminal transferase
Organism-1
Human
基因ID-1
1791
SwissProt-1
P04053
Organism-2
Mouse
SwissProt-2
P09838
背景
This gene is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, the encoded protein is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus .





