- 产品信息
商品描述
靶点-Target
TCP-1 ε
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
67kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human CCT5. AA range:241-290
特异性
TCP-1 ε Polyclonal Antibody detects endogenous levels of TCP-1 ε protein.
基因名称
CCT5
蛋白名称
T-complex protein 1 subunit epsilon
别名
CCT5;CCTE;KIAA0098;T-complex protein 1 subunit epsilon;TCP-1-epsilon;CCT-epsilon
Organism-1
Human
基因ID-1
22948
SwissProt-1
P48643
Organism-2
Mouse
基因ID-2
12465
SwissProt-2
P80316
Organism-3
Rat
基因ID-3
294864
SwissProt-3
Q68FQ0
背景
The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Mutations in this gene cause hereditary sensory and autonomic neuropathy with spastic paraplegia (HSNSP). Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 5 and 13. [provided by RefSeq, Apr 2015],
细胞定位
Cytoplasm . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome .





