FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
TCF-4/12
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
60kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human TCF4/12. AA range:581-630
特异性
TCF-4/12 Polyclonal Antibody detects endogenous levels of TCF-4/12 protein.
基因名称
TCF4/TCF12
蛋白名称
Transcription factor 4/12
别名
TCF4;BHLHB19;ITF2;SEF2;Transcription factor 4;TCF-4;Class B basic helix-loop-helix protein 19;bHLHb19;Immunoglobulin transcription factor 2;ITF-2;SL3-3 enhancer factor 2;SEF-2;TCF12;BHLHB20;HEB;HTF4;Transcription factor 12;
Organism-1
Human
基因ID-1
6925;6938
SwissProt-1
P15884;Q99081
Organism-2
Mouse
基因ID-2
21413;21406
Organism-3
Rat
基因ID-3
84382;25720
SwissProt-3
Q62655;P51514
背景
This gene encodes transcription factor 4, a basic helix-loop-helix transcription factor. The encoded protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers. This gene is broadly expressed, and may play an important role in nervous system development. Defects in this gene are a cause of Pitt-Hopkins syndrome. In addition, an intronic CTG repeat normally numbering 10-37 repeat units can expand to >50 repeat units and cause Fuchs endothelial corneal dystrophy. Multiple alternatively spliced transcript variants that encode different proteins have been described. [provided by RefSeq, Jul 2016],
细胞定位
Nucleus .
