T-cadherin Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2616457
- 产品信息
商品描述
靶点-Target
T-cadherin
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
78kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human CDH13. AA range:331-380
特异性
T-cadherin Polyclonal Antibody detects endogenous levels of T-cadherin protein.
基因名称
CDH13
蛋白名称
Cadherin-13
别名
CDH13;CDHH;Cadherin-13;Heart cadherin;H-cadherin;P105;Truncated cadherin;T-cad;T-cadherin
Organism-1
Human
基因ID-1
1012
SwissProt-1
P55290
Organism-2
Mouse
基因ID-2
12554
SwissProt-2
Q9WTR5
背景
This gene encodes a member of the cadherin superfamily. The encoded protein is localized to the surface of the cell membrane and is anchored by a GPI moiety, rather than by a transmembrane domain. The protein lacks the cytoplasmic domain characteristic of other cadherins, and so is not thought to be a cell-cell adhesion glycoprotein. This protein acts as a negative regulator of axon growth during neural differentiation. It also protects vascular endothelial cells from apoptosis due to oxidative stress, and is associated with resistance to atherosclerosis. The gene is hypermethylated in many types of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2011],
细胞定位
Cell membrane; Lipid-anchor, GPI-anchor.





