FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
TANK
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
48kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human TANK. AA range:171-220
特异性
TANK Polyclonal Antibody detects endogenous levels of TANK protein.
基因名称
TANK
蛋白名称
TRAF family member-associated NF-kappa-B activator
别名
TANK;ITRAF;TRAF2;TRAF family member-associated NF-kappa-B activator;TRAF-interacting protein;I-TRAF
Organism-1
Human
基因ID-1
10010
SwissProt-1
Q92844
Organism-2
Mouse
基因ID-2
21353
SwissProt-2
P70347
背景
The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily. The protein encoded by this gene is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby inhibiting TRAF function by sequestering the TRAFs in a latent state in the cytoplasm. For example, the protein encoded by this gene can block TRAF2 binding to LMP1, the Epstein-Barr virus transforming protein, and inhibit LMP1-mediated NF-kappa-B activation. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010],
细胞定位
Cytoplasm.
