- 产品信息
商品描述
靶点-Target
TAFI
反应性
Human,Rat,Mouse,
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
48kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human CPB2. AA range:321-370
特异性
TAFI Polyclonal Antibody detects endogenous levels of TAFI protein.
基因名称
CPB2
蛋白名称
Carboxypeptidase B2
别名
CPB2;Carboxypeptidase B2;Carboxypeptidase U;CPU;Plasma carboxypeptidase B;pCPB;Thrombin-activable fibrinolysis inhibitor;TAFI
Organism-1
Human
基因ID-1
1361
SwissProt-1
Q96IY4
Organism-2
Mouse
SwissProt-2
Q9JHH6
背景
Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). The protein encoded by this gene is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for this gene and its promoter region. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013],
细胞定位
Secreted.





