TAF II p135/p105 Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2616427

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商品描述
  • 靶点-Target

    TAF II p135/p105

  • 反应性

    Human,Mouse

  • 应用

    WB,IHC,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    110kD

  • 推荐稀释比

    WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human TAF4. AA range:941-990

  • 特异性

    TAF II p135/p105 Polyclonal Antibody detects endogenous levels of TAF II p135/p105 protein.

  • 基因名称

    TAF4/TAF4B

  • 蛋白名称

    Transcription initiation factor TFIID subunit 4/Transcription initiation factor TFIID subunit 4B

  • 别名

    TAF4;TAF2C;TAF2C1;TAF4A;TAFII130;TAFII135;Transcription initiation factor TFIID subunit 4;RNA polymerase II TBP-associated factor subunit C;TBP-associated factor 4;Transcription initiation factor TFIID 130 kDa subunit;TAF;II;130;

  • Organism-1

    Human

  • 基因ID-1

    6874;6875

  • SwissProt-1

    O00268;Q92750

  • 背景

    Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the larger subunits of TFIID that has been shown to potentiate transcriptional activation by retinoic acid, thyroid hormone and

  • 细胞定位

    Nucleus.