FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
TACE
反应性
Human,Mouse,Rat
应用
IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
93kD
推荐稀释比
IF 1:200-1:1000;ELISA 1:5000;Not yet tested in other applications;
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human ADAM 17. AA range:701-750
特异性
TACE Polyclonal Antibody detects endogenous levels of TACE protein.
基因名称
ADAM17
蛋白名称
Disintegrin and metalloproteinase domain-containing protein 17
别名
ADAM17;CSVP;TACE;Disintegrin and metalloproteinase domain-containing protein 17;ADAM 17;Snake venom-like protease;TNF-alpha convertase;TNF-alpha-converting enzyme;CD antigen CD156b
Organism-1
Human
基因ID-1
6868
SwissProt-1
P78536
Organism-2
Mouse
基因ID-2
11491
SwissProt-2
Q9Z0F8
Organism-3
Rat
基因ID-3
57027
SwissProt-3
Q9Z1K9
背景
ADAM metallopeptidase domain 17(ADAM17) Homo sapiens This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The encoded preproprotein is proteolytically processed to generate the mature protease. The encoded protease functions in the ectodomain shedding of tumor necrosis factor-alpha, in which soluble tumor necrosis factor-alpha is released from the membrane-bound precursor. This protease also functions in the processing of numerous other substrates, including cell adhesion proteins, cytokine and growth factor receptors and epidermal growth factor (EGF) receptor ligands. The encoded protein also plays a prominent role in the activation o
细胞定位
Membrane; Single-pass type I membrane protein.
