Synaptotagmin XI Polyclonal Antibody

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¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2616391

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商品描述
  • 靶点-Target

    Synaptotagmin XI

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    48kD

  • 推荐稀释比

    WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human SYT11. AA range:181-230

  • 特异性

    Synaptotagmin XI Polyclonal Antibody detects endogenous levels of Synaptotagmin XI protein.

  • 基因名称

    SYT11

  • 蛋白名称

    Synaptotagmin-11

  • 别名

    SYT11;KIAA0080;Synaptotagmin-11;Synaptotagmin XI;SytXI

  • Organism-1

    Human

  • 基因ID-1

    23208

  • SwissProt-1

    Q9BT88

  • Organism-2

    Mouse

  • 基因ID-2

    229521

  • SwissProt-2

    Q9R0N3

  • Organism-3

    Rat

  • SwissProt-3

    O08835

  • 背景

    synaptotagmin 11(SYT11) Homo sapiens This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that are known calcium sensors and mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. The encoded protein is also a substrate for ubiquitin-E3-ligase parkin. The gene has previously been referred to as synaptotagmin XII but has been renamed synaptotagmin XI to be consistent with mouse and rat official nomenclature. [provided by RefSeq, Apr 2010],

  • 细胞定位

    Cytoplasmic vesicle membrane ; Single-pass membrane protein . Perikaryon . Golgi apparatus, trans-Golgi network membrane ; Single-pass membrane protein . Recycling endosome membrane ; Single-pass membrane protein . Lysosome membrane ; Single-pass membrane protein . Cytoplasmic vesicle, phagosome . Cell projection, axon . Cell projection, dendrite . Cell junction, synapse, postsynaptic density . Recycling endosome membrane ; Single-pass membrane protein . Cytoplasmic vesicle, clathrin-coated vesicle membrane ; Single-pass membrane protein . Perikaryon . Localized in vesicles that travels in axonal and dendritic shafts in both anterograde and retrograde directions. In macrophages and microglia, recruited in phagosomes at early stages of phagocytosis (By similarity). Found in the core of the Lewy bodies in the brain of sporadic Parkinson disease patients (PubMed:12925569). .