- 产品信息
商品描述
靶点-Target
SURF-1
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
30kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human SURF1. AA range:171-220
特异性
SURF-1 Polyclonal Antibody detects endogenous levels of SURF-1 protein.
基因名称
SURF1
蛋白名称
Surfeit locus protein 1
别名
SURF1;SURF-1;Surfeit locus protein 1
Organism-1
Human
基因ID-1
6834
SwissProt-1
Q15526
Organism-2
Mouse
基因ID-2
20930
SwissProt-2
P09925
Organism-3
Rat
基因ID-3
64463
SwissProt-3
Q9QXU2
背景
This gene encodes a protein localized to the inner mitochondrial membrane and thought to be involved in the biogenesis of the cytochrome c oxidase complex. The protein is a member of the SURF1 family, which includes the related yeast protein SHY1 and rickettsial protein RP733. The gene is located in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity, where it shares a bidirectional promoter with SURF2 on the opposite strand. Defects in this gene are a cause of Leigh syndrome, a severe neurological disorder that is commonly associated with systemic cytochrome c oxidase deficiency. [provided by RefSeq, Jul 2008],
细胞定位
Mitochondrion inner membrane ; Multi-pass membrane protein .





