FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
SUMO-1
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
12kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human Sumo1. AA range:1-50
特异性
SUMO-1 Polyclonal Antibody detects endogenous levels of SUMO-1 protein.
基因名称
SUMO1
蛋白名称
Small ubiquitin-related modifier 1
别名
SUMO1;SMT3C;SMT3H3;UBL1;OK/SW-cl.43;Small ubiquitin-related modifier 1;SUMO-1;GAP-modifying protein 1;GMP1;SMT3 homolog 3;Sentrin;Ubiquitin-homology domain protein PIC1;Ubiquitin-like protein SMT3C;Smt3C;Ubiquitin-like protein
Organism-1
Human
基因ID-1
7341
SwissProt-1
P63165
Organism-2
Mouse
基因ID-2
22218
SwissProt-2
P63166
Organism-3
Rat
基因ID-3
301442
SwissProt-3
Q5I0H3
背景
This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last four amino acids of the carboxy-terminus have been cleaved off. Several pseudogenes have been reported for this gene. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus membrane . Nucleus speckle . Cytoplasm . Nucleus, PML body . Cell membrane . Nucleus . Recruited by BCL11A into the nuclear body (By similarity). In the presence of ZFHX3, sequesterd to nuclear body (NB)-like dots in the nucleus some of which overlap or closely associate with PML body (PubMed:24651376). .
