- 产品信息
商品描述
靶点-Target
STEAP2
反应性
Human,Mouse
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
56kD
推荐稀释比
WB 1:500-1:2000;IHC: 1:100-300;ELISA 1:20000;IF 1:100-300;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human STEA2. AA range:431-480
特异性
STEAP2 Polyclonal Antibody detects endogenous levels of STEAP2 protein.
基因名称
STEAP2
蛋白名称
Metalloreductase STEAP2
别名
STEAP2;PCANAP1;STAMP1;Metalloreductase STEAP2;Prostate cancer-associated protein 1;Protein up-regulated in metastatic prostate cancer;PUMPCn;Six-transmembrane epithelial antigen of prostate 2;SixTransMembrane protein of prostate 1
Organism-1
Human
基因ID-1
261729
SwissProt-1
Q8NFT2
Organism-2
Mouse
基因ID-2
74051
SwissProt-2
Q8BWB6
背景
STEAP2 metalloreductase(STEAP2) Homo sapiens This gene is a member of the STEAP family and encodes a multi-pass membrane protein that localizes to the Golgi complex, the plasma membrane, and the vesicular tubular structures in the cytosol. A highly similar protein in mouse has both ferrireductase and cupric reductase activity, and stimulates the cellular uptake of both iron and copper in vitro. Increased transcriptional expression of the human gene is associated with prostate cancer progression. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008],
细胞定位
Endosome membrane ; Multi-pass membrane protein . Cell membrane ; Multi-pass membrane protein .





