FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Stat4
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,IP,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
85kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IP 2-5 ug:mg lysate;ELISA 1:5000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human STAT4. AA range:660-709
特异性
Stat4 Polyclonal Antibody detects endogenous levels of Stat4 protein.
基因名称
STAT4
蛋白名称
Signal transducer and activator of transcription 4
别名
STAT4;Signal transducer and activator of transcription 4
Organism-1
Human
基因ID-1
6775
SwissProt-1
Q14765
Organism-2
Mouse
基因ID-2
20849
SwissProt-2
P42228
背景
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011],
细胞定位
Cytoplasm. Nucleus. Translocated into the nucleus in response to phosphorylation.
