FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
STAG3
反应性
Human,Rat,Mouse,
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
139kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human STAG3. AA range:1161-1210
特异性
STAG3 Polyclonal Antibody detects endogenous levels of STAG3 protein.
基因名称
STAG3
蛋白名称
Cohesin subunit SA-3
别名
STAG3;Cohesin subunit SA-3;SCC3 homolog 3;Stromal antigen 3;Stromalin-3
Organism-1
Human
基因ID-1
10734
SwissProt-1
Q9UJ98
Organism-2
Mouse
SwissProt-2
O70576
背景
The protein encoded by this gene is expressed in the nucleus and is a subunit of the cohesin complex which regulates the cohesion of sister chromatids during cell division. A mutation in this gene is associated with premature ovarian failure. Alternate splicing results in multiple transcript variants encoding distinct isoforms. This gene has multiple pseudogenes. [provided by RefSeq, Apr 2014],
细胞定位
Nucleus . Chromosome . Chromosome, centromere . Associates with chromatin. In prophase I stage of meiosis, it is found along the axial elements of synaptonemal complexes. In late-pachytene-diplotene, the bulk of protein dissociates from the chromosome arms probably because of phosphorylation by PLK1, except at centromeres, where cohesin complexes remain. It however remains chromatin associated at the centromeres up to metaphase I. During anaphase I, it probably dissociates from centromeres, allowing chromosomes segregation. .
