FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
ST5
反应性
Human,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
126kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human ST5. AA range:411-460
特异性
ST5 Polyclonal Antibody detects endogenous levels of ST5 protein.
基因名称
ST5
蛋白名称
Suppression of tumorigenicity 5 protein
别名
ST5;DENND2B;HTS1;Suppression of tumorigenicity 5 protein;DENN domain-containing protein 2B;HeLa tumor suppression 1
Organism-1
Human
基因ID-1
6764
SwissProt-1
P78524
Organism-2
Mouse
基因ID-2
76954
SwissProt-2
Q924W7
背景
This gene was identified by its ability to suppress the tumorigenicity of Hela cells in nude mice. The protein encoded by this gene contains a C-terminal region that shares similarity with the Rab 3 family of small GTP binding proteins. This protein preferentially binds to the SH3 domain of c-Abl kinase, and acts as a regulator of MAPK1/ERK2 kinase, which may contribute to its ability to reduce the tumorigenic phenotype in cells. Three alternatively spliced transcript variants of this gene encoding distinct isoforms are identified. [provided by RefSeq, Jul 2008],
细胞定位
[Isoform 1]: Cytoplasm, cell cortex . Cell membrane . Recycling endosome . Colocalizes with RAB13 and ITSN1 at cytoplasmic vesicles that are most likely recycling endosomes. Colocalizes with the cortical actin cytoskeleton. .
