- 产品信息
商品描述
靶点-Target
SR-4
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
43kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:5000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human 5-HT-4. AA range:21-70
特异性
SR-4 Polyclonal Antibody detects endogenous levels of SR-4 protein.
基因名称
HTR4
蛋白名称
5-hydroxytryptamine receptor 4
别名
HTR4;5-hydroxytryptamine receptor 4;5-HT-4;5-HT4;Serotonin receptor 4
Organism-1
Human
基因ID-1
3360
SwissProt-1
Q13639
Organism-2
Mouse
基因ID-2
15562
SwissProt-2
P97288
Organism-3
Rat
基因ID-3
25324
SwissProt-3
Q62758
背景
This gene is a member of the family of serotonin receptors, which are G protein coupled receptors that stimulate cAMP production in response to serotonin (5-hydroxytryptamine). The gene product is a glycosylated transmembrane protein that functions in both the peripheral and central nervous system to modulate the release of various neurotransmitters. Multiple transcript variants encoding proteins with distinct C-terminal sequences have been described. [provided by RefSeq, May 2010],
细胞定位
Cell membrane; Multi-pass membrane protein. Endosome. Interaction with SNX27 mediates recruitment to early endosomes, while interaction with SLC9A3R1 and EZR might target the protein to specialized subcellular regions, such as microvilli. .





