FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
SR-2C
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
55kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:5000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human 5-HT-2C. AA range:161-210
特异性
SR-2C Polyclonal Antibody detects endogenous levels of SR-2C protein.
基因名称
HTR2C
蛋白名称
5-hydroxytryptamine receptor 2C
别名
HTR2C;HTR1C;5-hydroxytryptamine receptor 2C;5-HT-2C;5-HT2C;5-HTR2C;5-hydroxytryptamine receptor 1C;5-HT-1C;5-HT1C;Serotonin receptor 2C
Organism-1
Human
基因ID-1
3358
SwissProt-1
P28335
Organism-2
Mouse
基因ID-2
15560
SwissProt-2
P34968
Organism-3
Rat
基因ID-3
25187
SwissProt-3
P08909
背景
This gene encodes a seven-transmembrane G-protein-coupled receptor. The encoded protein responds to signaling through the neurotransmitter serotonin. The mRNA of this gene is subject to multiple RNA editing events, where adenosine residues encoded by the genome are converted to inosines. RNA editing is predicted to alter the structure of the second intracellular loop, thereby generating alternate protein forms with decreased ability to interact with G proteins. Abnormalities in RNA editing of this gene have been detected in victims of suicide that suffer from depression. In addition, naturally-occuring variation in the promoter and 5' non-coding and coding regions of this gene may show statistically-significant association with mental illness and behavioral disorders. Alternative splicing results in multiple different transcript variants. [provided by RefSeq, Jan 2015],
细胞定位
Cell membrane ; Multi-pass membrane protein .
