- 产品信息
商品描述
靶点-Target
SR-2B
反应性
Human
应用
WB,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
54kD
推荐稀释比
WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human HTR2B. AA range:15-64
特异性
SR-2B Polyclonal Antibody detects endogenous levels of SR-2B protein.
基因名称
HTR2B
蛋白名称
5-hydroxytryptamine receptor 2B
别名
HTR2B;5-hydroxytryptamine receptor 2B;5-HT-2B;5-HT2B;Serotonin receptor 2B
Organism-1
Human
基因ID-1
3357
SwissProt-1
P41595
Organism-2
Mouse
SwissProt-2
Q02152
背景
This gene encodes one of the several different receptors for 5-hydroxytryptamine (serotonin) that belongs to the G-protein coupled receptor 1 family. Serotonin is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin receptors mediate many of the central and peripheral physiologic functions of serotonin, including regulation of cardiovascular functions and impulsive behavior. Population and family-based analyses of a minor allele (glutamine-to-stop substitution, designated Q20*) which blocks expression of this protein, and knockout studies in mice, suggest a role for this gene in impulsivity. However, other factors, such as elevated testosterone levels, may also be involved. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2016],
细胞定位
Cell membrane ; Multi-pass membrane protein . Cell junction, synapse, synaptosome .





