FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
SPT16
反应性
Human,Mouse
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
119kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human SUPT16H. AA range:941-990
特异性
SPT16 Polyclonal Antibody detects endogenous levels of SPT16 protein.
基因名称
SUPT16H
蛋白名称
FACT complex subunit SPT16
别名
SUPT16H;FACT140;FACTP140;FACT complex subunit SPT16;Chromatin-specific transcription elongation factor 140 kDa subunit;FACT 140 kDa subunit;FACTp140;Facilitates chromatin transcription complex subunit SPT16;hSPT16
Organism-1
Human
基因ID-1
11198
SwissProt-1
Q9Y5B9
Organism-2
Mouse
基因ID-2
114741
SwissProt-2
Q920B9
背景
Transcription of protein-coding genes can be reconstituted on naked DNA with only the general transcription factors and RNA polymerase II. However, this minimal system cannot transcribe DNA packaged into chromatin, indicating that accessory factors may facilitate access to DNA. One such factor, FACT (facilitates chromatin transcription), interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT is composed of an 80 kDa subunit and a 140 kDa subunit; this gene encodes the 140 kDa subunit. [provided by RefSeq, Feb 2009],
细胞定位
Nucleus . Chromosome . Colocalizes with RNA polymerase II on chromatin. Recruited to actively transcribed loci.
