Spectrin β II Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2616308
- 产品信息
商品描述
靶点-Target
Spectrin β II
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
275kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human SPTBN1. AA range:651-700
特异性
Spectrin β II Polyclonal Antibody detects endogenous levels of Spectrin β II protein.
基因名称
SPTBN1
蛋白名称
Spectrin beta chain non-erythrocytic 1
别名
SPTBN1;SPTB2;Spectrin beta chain;non-erythrocytic 1;Beta-II spectrin;Fodrin beta chain;Spectrin, non-erythroid beta chain 1
Organism-1
Human
基因ID-1
6711
SwissProt-1
Q01082
Organism-2
Mouse
基因ID-2
20742
SwissProt-2
Q62261
背景
Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is composed of two antiparallel dimers of alpha- and beta- subunits. This gene is one member of a family of beta-spectrin genes. The encoded protein contains an N-terminal actin-binding domain, and 17 spectrin repeats which are involved in dimer formation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm, cytoskeleton . Cytoplasm, myofibril, sarcomere, M line . Colocalizes with ANK2 in a distinct intracellular compartment of neonatal cardiomyocytes. .; [Isoform 2]: Cell membrane ; Peripheral membrane protein ; Cytoplasmic side .





