FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
SP-B
反应性
Human,Rat,Mouse,
应用
WB,ELISA,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
42kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human SP-B. AA range:243-292
特异性
SP-B Polyclonal Antibody detects endogenous levels of SP-B protein.
基因名称
SFTPB
蛋白名称
Pulmonary surfactant-associated protein B
别名
SFTPB;SFTP3;Pulmonary surfactant-associated protein B;SP-B;18 kDa pulmonary-surfactant protein;6 kDa protein;Pulmonary surfactant-associated proteolipid SPL;Phe;
Organism-1
Human
基因ID-1
6439
SwissProt-1
P07988
Organism-2
Mouse
SwissProt-2
P50405
背景
This gene encodes the pulmonary-associated surfactant protein B (SPB), an amphipathic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90% lipids and 10% proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. The SPB enhances the rate of spreading and increases the stability of surfactant monolayers in vitro. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 1, also called pulmonary alveolar proteinosis due to surfactant protein B deficiency, and are associated with fatal respiratory distress in the neonatal period. Alternatively spliced trans
细胞定位
Secreted, extracellular space, surface film.
