SPAK Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2616306

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商品描述
  • 靶点-Target

    SPAK

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,IHC,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    60kD

  • 推荐稀释比

    WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human STK39. AA range:277-326

  • 特异性

    SPAK Polyclonal Antibody detects endogenous levels of SPAK protein.

  • 基因名称

    STK39

  • 蛋白名称

    STE20/SPS1-related proline-alanine-rich protein kinase

  • 别名

    STK39;SPAK;STE20/SPS1-related proline-alanine-rich protein kinase;Ste-20-related kinase;DCHT;Serine/threonine-protein kinase 39

  • Organism-1

    Human

  • 基因ID-1

    27347

  • SwissProt-1

    Q9UEW8

  • Organism-2

    Mouse

  • 基因ID-2

    53416

  • SwissProt-2

    Q9Z1W9

  • Organism-3

    Rat

  • 基因ID-3

    54348

  • SwissProt-3

    O88506

  • 背景

    This gene encodes a serine/threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation-chloride-coupled cotransporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the response to cellular stress. [provided by RefSeq, Jul 2008],

  • 细胞定位

    Cytoplasm . Nucleus . Nucleus when caspase-cleaved. .