FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Socius
反应性
Human,Rat,Mouse,
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
57kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human UBXD5. AA range:131-180
特异性
Socius Polyclonal Antibody detects endogenous levels of Socius protein.
基因名称
UBXN11
蛋白名称
UBX domain-containing protein 11
别名
UBXN11;SOC;UBXD5;PP2243;UBX domain-containing protein 11;Colorectal tumor-associated antigen COA-1;Socius;UBX domain-containing protein 5
Organism-1
Human
基因ID-1
91544
SwissProt-1
Q5T124
Organism-2
Mouse
SwissProt-2
Q9D572
背景
This gene encodes a protein with a divergent C-terminal UBX domain. The homologous protein in the rat interacts with members of the Rnd subfamily of Rho GTPases at the cell periphery through its C-terminal region. It also interacts with several heterotrimeric G proteins through their G-alpha subunits and promotes Rho GTPase activation. It is proposed to serve a bidirectional role in the promotion and inhibition of Rho activity through upstream signaling pathways. The 3' coding sequence of this gene contains a polymoprhic region of 24 nt tandem repeats. Several transcripts containing between 1.5 and five repeat units have been reported. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm, cytoskeleton .
