FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
SnoN
反应性
Human,Mouse
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
77kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human SKIL. AA range:616-665
特异性
SnoN Polyclonal Antibody detects endogenous levels of SnoN protein.
基因名称
SKIL
蛋白名称
Ski-like protein
别名
SKIL;SNO;Ski-like protein;Ski-related oncogene;Ski-related protein
Organism-1
Human
基因ID-1
6498
SwissProt-1
P12757
Organism-2
Mouse
基因ID-2
20482
SwissProt-2
Q60665
背景
The protein encoded by this gene is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor-beta (TGFB). In the absence of ligand, the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex. TGFB signaling causes SMAD3 to enter the nucleus and degrade this protein, allowing these genes to be activated. Four transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Oct 2011],
细胞定位
acrosomal vesicle,nucleus,nucleoplasm,transcription factor complex,cytoplasm,PML body,transcriptional repressor complex,protein complex,
