- 产品信息
商品描述
靶点-Target
sMtCK
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
48kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:40000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human CKMT2. AA range:231-280
特异性
sMtCK Polyclonal Antibody detects endogenous levels of sMtCK protein.
基因名称
CKMT2
蛋白名称
Creatine kinase S-type mitochondrial
别名
CKMT2;Creatine kinase S-type;mitochondrial;Basic-type mitochondrial creatine kinase;Mib-CK;Sarcomeric mitochondrial creatine kinase;S-MtCK
Organism-1
Human
基因ID-1
1160
SwissProt-1
P17540
Organism-2
Mouse
基因ID-2
76722
SwissProt-2
Q6P8J7
Organism-3
Rat
SwissProt-3
P09605
背景
creatine kinase, mitochondrial 2(CKMT2) Homo sapiens Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Sarcomeric mitochondrial creatine kinase has 80% homology with the coding exons of ubiquitous mitochondrial creatine kinase. This gene contains sequences homologous to several motifs that are shared among some nuclear genes encoding mitochondrial proteins and thus may be essential for the coordinated activation of these genes during mitochondrial biogenesis. Three transcript variants encoding the same protein have been found for this gen
细胞定位
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.





