SMRTe Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2616276

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商品描述
  • 靶点-Target

    SMRTe

  • 反应性

    Human,Mouse

  • 应用

    IHC,IF,WB,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    270kD

  • 推荐稀释比

    WB 1:500-2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human NCOR2. AA range:511-560

  • 特异性

    SMRTe Polyclonal Antibody detects endogenous levels of SMRTe protein.

  • 基因名称

    NCOR2

  • 蛋白名称

    Nuclear receptor corepressor 2

  • 别名

    NCOR2;CTG26;Nuclear receptor corepressor 2;N-CoR2;CTG repeat protein 26;SMAP270;Silencing mediator of retinoic acid and thyroid hormone receptor;SMRT;T3 receptor-associating factor;TRAC;Thyroid-;retinoic-acid-receptor-associated

  • Organism-1

    Human

  • 基因ID-1

    9612

  • SwissProt-1

    Q9Y618

  • Organism-2

    Mouse

  • SwissProt-2

    Q9WU42

  • 背景

    This gene encodes a nuclear receptor co-repressor that mediates transcriptional silencing of certain target genes. The encoded protein is a member of a family of thyroid hormone- and retinoic acid receptor-associated co-repressors. This protein acts as part of a multisubunit complex which includes histone deacetylases to modify chromatin structure that prevents basal transcriptional activity of target genes. Aberrant expression of this gene is associated with certain cancers. Alternate splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Apr 2011],

  • 细胞定位

    Nucleus.