- 产品信息
商品描述
靶点-Target
SLU7
反应性
Human,Mouse,Rat
应用
WB,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
65kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human SLU7. AA range:113-162
特异性
SLU7 Polyclonal Antibody detects endogenous levels of SLU7 protein.
基因名称
SLU7
蛋白名称
Pre-mRNA-splicing factor SLU7
别名
SLU7;Pre-mRNA-splicing factor SLU7;hSlu7
Organism-1
Human
基因ID-1
10569
SwissProt-1
O95391
Organism-2
Mouse
基因ID-2
193116
SwissProt-2
Q8BHJ9
Organism-3
Rat
基因ID-3
303057
SwissProt-3
Q80ZG5
背景
Pre-mRNA splicing occurs in two sequential transesterification steps. The protein encoded by this gene is a splicing factor that has been found to be essential during the second catalytic step in the pre-mRNA splicing process. It associates with the spliceosome and contains a zinc knuckle motif that is found in other splicing factors and is involved in protein-nucleic acid and protein-protein interactions. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus . Nucleus speckle . Cytoplasm . Predominantly nuclear. Shuttling between the nucleus and the cytoplasm is regulated by the CCHC-type zinc finger. Upon UV-C stress stimulus, the nuclear concentration of the protein decreases, affecting alternative splicing. Translocates from the nucleus to the cytoplasm after heat shock cell treatment. Accumulates in cytoplasmic vesicle-like organelles after heat shock treatment, which may represent stress granules. .





