FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Skp1 p19
反应性
Human,Mouse,Rat,Monkey
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
19kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human SKP1A/p19. AA range:41-90
特异性
Skp1 p19 Polyclonal Antibody detects endogenous levels of Skp1 p19 protein.
基因名称
SKP1
蛋白名称
S-phase kinase-associated protein 1
别名
SKP1;EMC19;OCP2;SKP1A;TCEB1L;S-phase kinase-associated protein 1;Cyclin-A/CDK2-associated protein p19;Organ of Corti protein 2;OCP-2;Organ of Corti protein II;OCP-II;RNA polymerase II elongation factor-like protein;SIII;Transcr
Organism-1
Human
基因ID-1
6500
SwissProt-1
P63208
Organism-2
Mouse
基因ID-2
21402
SwissProt-2
Q9WTX5
Organism-3
Rat
基因ID-3
287280
SwissProt-3
Q6PEC4
背景
This gene encodes a component of SCF complexes, which are composed of this protein, cullin 1, a ring-box protein, and one member of the F-box family of proteins. This protein binds directly to the F-box motif found in F-box proteins. SCF complexes are involved in the regulated ubiquitination of specific protein substrates, which targets them for degradation by the proteosome. Specific F-box proteins recognize different target protein(s), and many specific SCF substrates have been identified including regulators of cell cycle progression and development. Studies have also characterized the protein as an RNA polymerase II elongation factor. Alternative splicing of this gene results in two transcript variants. A related pseudogene has been identified on chromosome 7. [provided by RefSeq, Jul 2008],
细胞定位
nucleus,nucleoplasm,cytoplasm,centrosome,cytosol,SCF ubiquitin ligase complex,Cul7-RING ubiquitin ligase complex,PcG protein complex,extracellular exosome,
