FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
SKI-1
反应性
Human,Mouse,Rat
应用
WB,ELISA,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
130kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from SKI-1 . at AA range: 180-260
特异性
SKI-1 Polyclonal Antibody detects endogenous levels of SKI-1 protein.
基因名称
MBTPS1
蛋白名称
Membrane-bound transcription factor site-1 protease
别名
MBTPS1;KIAA0091;S1P;SKI1;Membrane-bound transcription factor site-1 protease;Endopeptidase S1P;Subtilisin/kexin-isozyme 1;SKI-1
Organism-1
Human
基因ID-1
8720
SwissProt-1
Q14703
Organism-2
Mouse
基因ID-2
56453
SwissProt-2
Q9WTZ2
Organism-3
Rat
基因ID-3
89842
SwissProt-3
Q9WTZ3
背景
This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to the cis/medial-Golgi where a second autocatalytic event takes place and the catalytic activity is acquired. It encodes a type 1 membrane bound protease which is ubiquitously expressed and regulates cholesterol or lipid homeostasis via cleavage of substrates at non-basic residues. Mutations in this gene may be associated with lysosomal dysfunction. [provided by RefSeq, Feb 2014],
细胞定位
Endoplasmic reticulum membrane ; Single-pass type I membrane protein . Golgi apparatus membrane ; Single-pass type I membrane protein . May sort to other organelles, including lysosomal and/or endosomal compartments. .
