- 产品信息
商品描述
靶点-Target
Siah-2
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
38kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human SIAH2. AA range:241-290
特异性
Siah-2 Polyclonal Antibody detects endogenous levels of Siah-2 protein.
基因名称
SIAH2
蛋白名称
E3 ubiquitin-protein ligase SIAH2
别名
SIAH2;E3 ubiquitin-protein ligase SIAH2;Seven in absentia homolog 2;Siah-2;hSiah2
Organism-1
Human
基因ID-1
6478
SwissProt-1
O43255
Organism-2
Mouse
基因ID-2
20439
SwissProt-2
Q06986
Organism-3
Rat
基因ID-3
140593
SwissProt-3
Q8R4T2
背景
This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in regulating cellular response to hypoxia. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm . Nucleus . Predominantly cytoplasmic. Partially nuclear. .





