- 产品信息
商品描述
靶点-Target
SgK269
反应性
Human,Mouse
应用
WB,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
195kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human SGK269. AA range:111-160
特异性
SgK269 Polyclonal Antibody detects endogenous levels of SgK269 protein.
基因名称
PEAK1
蛋白名称
Pseudopodium-enriched atypical kinase 1
别名
PEAK1;KIAA2002;Pseudopodium-enriched atypical kinase 1;Sugen kinase 269;Tyrosine-protein kinase SgK269
Organism-1
Human
基因ID-1
79834
SwissProt-1
Q9H792
Organism-2
Mouse
SwissProt-2
Q69Z38
背景
This gene encodes a non-receptor tyrosine kinase that is a member of the new kinase family three (NFK3) family. In migrating cells, the encoded protein is associated with the actin cytoskeleton and focal adhesions and promotes developing focal adhesion elongation. This protein may play a role in the regulation of cell migration, proliferation and cancer metastasis. [provided by RefSeq, Mar 2014],
细胞定位
Cytoplasm, cytoskeleton . Cell junction, focal adhesion . Colocalizes with F-actin in serum-rich medium (PubMed:20534451). Actin colocalization is reduced during serum starvation (PubMed:20534451). .





